Description

D-Timolol Maleate CAS NO 26839-77-0 is a high-purity, non-racemic enantiomer of the β-adrenergic blocking agent Timolol. This specific stereoisomer is of significant value in pharmaceutical research and development, particularly for studying structure-activity relationships and developing novel therapeutic agents. It is primarily required by pharmaceutical companies, advanced research institutions, and fine chemical manufacturers engaged in the synthesis of chiral drugs and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and synthesis of enantiomerically pure β-blocker medications.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate β-adrenergic receptor interactions and selectivity.
• Analytical Standard: Serves as a high-purity standard for quality control and analytical method development (e.g., HPLC, Chiral Chromatography) in pharmaceutical laboratories.
• Process Development: Employed in the development and optimization of asymmetric synthesis routes for complex chiral molecules.
• Academic Research: Utilized in university and institutional research projects focused on cardiovascular drug mechanisms and stereochemistry.

Basic Information

Item	Detail
Product Name	D-Timolol Maleate
CAS No.	26839-77-0
Molecular Formula	C17H24N4O3S • C4H4O4
Molecular Weight	432.49 g/mol
Synonyms	(-)-Timolol Maleate; (S)-Timolol Maleate; D-(-)-Timolol Maleate; (S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol Maleate; Levobunolol Impurity C (Maleate); Timolol Maleate Enantiomer (D-form); Timolol EP Impurity C Maleate
EINECS	Contact for details

Quality Control

Our D-Timolol Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, identification, and impurity profiling, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.