Description

4-Amino-1-[2,3,6-Trideoxy-4-o-[4,6-Dideoxy-4-Dimethylamino-α-D-Glucopyranosyl]-β-D-Erythro-Hexopyranosyl]Pyrimidin-2(1H)-One is a complex nucleoside analog with significant biological activity, primarily known as a key intermediate in the synthesis of potent antiviral and anticancer agents. Its intricate glycosidic structure makes it a valuable building block for advanced pharmaceutical research and development. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on novel therapeutic development.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of nucleoside-based antiviral drugs.
• Anticancer Research: Serves as a scaffold for developing novel chemotherapeutic agents targeting DNA/RNA synthesis.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate nucleotide metabolism pathways.
• Antiviral Agent Development: Key starting material for the production of compounds active against a range of viral targets.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	4-Amino-1-[2,3,6-Trideoxy-4-o-[4,6-Dideoxy-4-Dimethylamino-α-D-Glucopyranosyl]-β-D-Erythro-Hexopyranosyl]Pyrimidin-2(1H)-One
CAS No.	26758-91-8
Molecular Formula	C₁₇H₂₈N₄O₇
Molecular Weight	400.43 g/mol
Synonyms	4-Amino-1-(2,3,6-trideoxy-4-O-[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]-β-D-erythro-hexopyranosyl)pyrimidin-2(1H)-one; Daunosaminylcytosine; 4-Amino-1-(2,3,6-trideoxy-4-O-[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]-β-D-erythro-hexopyranosyl)-2(1H)-pyrimidinone; 1-(2,3,6-Trideoxy-4-O-[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]-β-D-erythro-hexopyranosyl)cytosine; NSC 329514; Antibiotic DC 92; Cytosine daunosaminide
EINECS	Contact for details

Quality Control

Our 4-Amino-1-[2,3,6-Trideoxy-4-o-[4,6-Dideoxy-4-Dimethylamino-α-D-Glucopyranosyl]-β-D-Erythro-Hexopyranosyl]Pyrimidin-2(1H)-One is manufactured under strict quality systems suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and MS for structural confirmation, and comprehensive impurity profiling. Certificates of Analysis (COA) documenting full specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.