Description

4-Amino-2-Fluorobutanoic Acid Hydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated peptide-based drugs and enzyme inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to introduce fluorine atoms, which can modulate bioavailability, metabolic stability, and binding affinity.
• Peptidomimetics: Serves as a constrained amino acid analog for constructing novel peptide backbones with enhanced pharmacological properties.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate biological pathways.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, fluorinated active ingredients for crop protection.
• Material Science: Can be incorporated into specialized polymers or coatings to impart unique chemical properties.

Basic Information

Product Name	4-Amino-2-Fluorobutanoic Acid Hydrochloride
CAS No.	26437-22-9
Molecular Formula	C4H9FNO2 • HCl
Molecular Weight	155.58 (Free base) / 192.04 (Hydrochloride salt)
Synonyms	2-Fluoro-4-aminobutanoic acid hydrochloride; (R/S)-4-Amino-2-fluorobutanoic acid hydrochloride; 4-Amino-2-fluorobutyric acid HCl; DL-4-Amino-2-fluorobutanoic acid hydrochloride; FAOB-OH • HCl; γ-Amino-β-fluorobutyric acid hydrochloride; 4-Amino-2-fluoro-butanoic acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Fluorobutanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.