Description

S(-)-Pindolol is the pharmacologically active enantiomer of the non-selective β-adrenergic receptor blocker pindolol. This high-purity chiral building block is critical for research and development in stereospecific pharmaceuticals. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on cardiovascular and central nervous system drug discovery. Our supply ensures consistent enantiomeric excess for reliable experimental and process-scale outcomes.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of enantiomerically pure β-blocker medications.
• Biochemical Research: Used as a reference standard and active agent in studies of β-adrenergic receptor binding and function.
• Metabolite Studies: Employed in the investigation of stereoselective drug metabolism and pharmacokinetics.
• Analytical Standard: Serves as a high-purity calibrant for HPLC, LC-MS, and other chromatographic methods in quality control laboratories.
• Asymmetric Synthesis: A valuable starting material or model compound for developing new chiral synthesis and resolution techniques.

Basic Information

Product Name	S(-)-Pindolol
CAS No.	26328-11-0
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	(S)-(-)-Pindolol; (-)-Pindolol; Levopindolol; (S)-1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol; (2S)-1-(1H-Indol-4-yloxy)-3-(isopropylamino)propan-2-ol; Visken (enantiomer); LB-46; Pindolol S-(-) enantiomer
EINECS	Contact for details

Quality Control

Our S(-)-Pindolol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and identification, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.