Description

2,6-Bis(Trifluoromethyl)Benzonitrile is a high-value fluorinated aromatic building block characterized by its electron-withdrawing trifluoromethyl groups and reactive nitrile functionality. This compound matters for its role in facilitating the synthesis of complex molecules with enhanced stability, lipophilicity, and biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 groups improve metabolic stability and membrane permeability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Development: Incorporated into the design of liquid crystals, organic semiconductors, and polymers to tune electronic properties and thermal stability.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions and constructing complex molecular architectures.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Benzonitrile
CAS No.	25753-25-7
Molecular Formula	C9H3F6N
Molecular Weight	239.12 g/mol
Synonyms	2,6-Bis(trifluoromethyl)benzonitrile; 2,6-Di(trifluoromethyl)benzonitrile; α,α,α,α',α',α'-Hexafluoro-o-tolunitrile; 2,6-Bis(trifluoromethyl)phenyl cyanide; Benzonitrile, 2,6-bis(trifluoromethyl)-; 2,6-BTFBN; 2,6-DTFBN; 25753-25-7
EINECS	Contact for details

Quality Control

Our 2,6-Bis(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.