Description

(2β,5α,12S,19α)-6α,21-Epoxy-17-Methoxyaspidospermidine is a complex indole alkaloid derivative belonging to the aspidosperma class, characterized by its specific stereochemistry and epoxy-methoxy functionalization. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate molecular architecture, which serves as a valuable scaffold for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of potential therapeutic agents targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex natural products and investigational new drugs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop novel analogs with potential biological activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology, total synthesis projects, and alkaloid chemistry.
• Process Chemistry Development: Acts as a critical intermediate in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	(2β,5α,12S,19α)-6α,21-Epoxy-17-Methoxyaspidospermidine
CAS No.	25480-48-2
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	17-Methoxyaspidospermidine-6α,21-epoxide; 6α,21-Epoxy-17-methoxyaspidospermidine; Aspidospermidine, 6α,21-epoxy-17-methoxy-; (2β,5α,12S,19α)-6α,21-Epoxy-17-methoxyaspidospermidine; NSC 338258; 17-Methoxy-6α,21-epoxyaspidospermidine
EINECS	Contact for details

Quality Control

Our (2β,5α,12S,19α)-6α,21-Epoxy-17-Methoxyaspidospermidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.