Description

4-(Difluoromethylthio)Nitrobenzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring both a difluoromethylthio and a nitro group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a building block for advanced polymers and liquid crystals, where the difluoromethylthio group can influence material properties like dielectric constant and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic aromatic substitutions to introduce functionalized aryl groups into more complex molecular architectures.

Basic Information

Product Name	4-(Difluoromethylthio)Nitrobenzene
CAS No.	24933-57-1
Molecular Formula	C7H5F2NO2S
Molecular Weight	205.18 g/mol
Synonyms	1-Nitro-4-(difluoromethylthio)benzene; p-(Difluoromethylthio)nitrobenzene; 4-Nitrophenyl difluoromethyl sulfide; Benzene, 1-(difluoromethylthio)-4-nitro-; NSC 403119
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethylthio)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.