Description

6-Hydroxybetamethasone is a significant synthetic corticosteroid derivative, primarily recognized as a key pharmaceutical intermediate. Its value lies in its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs), where precise chemical structure is critical for biological activity. This compound is essential for manufacturers in the pharmaceutical and research and development sectors, particularly those focused on developing anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of advanced corticosteroid APIs.
• Research & Development: Used in medicinal chemistry for the study of steroid structure-activity relationships and the development of new therapeutic agents.
• Reference Standard: Serves as an analytical standard in quality control laboratories for the identification and quantification of related steroid compounds.
• Biochemical Research: Employed in studies investigating glucocorticoid receptor interactions and metabolic pathways.

Basic Information

Product Name	6-Hydroxybetamethasone
CAS No.	24703-00-2
Molecular Formula	C₂₂H₂₉FO₆
Molecular Weight	408.46 g/mol
Synonyms	9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 6α-Hydroxybetamethasone; 6-Hydroxy-9α-fluoro-16β-methylprednisolone; Betamethasone, 6-hydroxy-; (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 6-Hydroxybetamethasone is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.