Description

Antazoline Sulfate is a high-purity pharmaceutical-grade active pharmaceutical ingredient (API) and chemical intermediate. This compound is valued for its potent antihistaminic and anticholinergic properties, making it a critical component in the development of ophthalmic and topical medicinal formulations. It is essential for manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors requiring a reliable and consistent raw material for research, development, and production.

Application

• Primary Pharmaceutical Ingredient: Key API in the formulation of ophthalmic solutions and nasal sprays for allergic conjunctivitis and rhinitis.
• Topical Medicinal Preparations: Used in creams and ointments designed for allergic skin conditions and minor irritations.
• Chemical Reference Standard: Serves as a certified standard for quality control and analytical method development in pharmaceutical laboratories.
• Research & Development: A vital compound for pharmacological studies, preclinical research, and the development of new antihistamine therapies.
• Veterinary Pharmaceuticals: Employed in formulations for treating allergic reactions in animals.
• Fine Chemical Synthesis: Acts as a sophisticated building block or intermediate in the synthesis of more complex organic molecules.

Basic Information

Product Name	Antazoline Sulfate
CAS No.	24359-81-7
Molecular Formula	C17H19N3 · H2SO4
Molecular Weight	363.42 g/mol
Synonyms	Antazoline Sulphate; 2-[(N-Benzylanilino)methyl]-2-imidazoline Sulfate; Phenazoline Sulfate; Antasten; Antistin; Azalone; N,N-Dimethyl-N-(phenylmethyl)-N-(2-imidazolin-2-ylmethyl)amine Sulfate
EINECS	Contact for details

Quality Control

Our Antazoline Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.