Description

Homochlorocyclizine Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient of significant commercial and research importance. Its primary value lies in its role as a key building block for the synthesis of antihistaminic and anticholinergic agents, offering reliable performance in complex chemical processes. This compound is essential for manufacturers and research institutions in the pharmaceutical, fine chemical, and life science sectors requiring precise and consistent raw materials for drug development and production.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antihistamine and anticholinergic active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry research for developing new therapeutic agents targeting histamine and acetylcholine receptors.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with specific pharmacological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of drug substances.

Basic Information

Item	Details
Product Name	Homochlorocyclizine Hydrochloride
CAS No.	24342-55-0
Molecular Formula	C19H23ClN2 • HCl
Molecular Weight	343.32 g/mol
Synonyms	1-(p-Chlorobenzhydryl)-4-methylpiperazine Dihydrochloride; Homochlorcyclizine Dihydrochloride; Homochlorcyclizine HCl; 1-[(4-Chlorophenyl)-phenylmethyl]-4-methylpiperazine Dihydrochloride; Homochlorocyclizine 2HCl; NSC 106977; SKF-5116
EINECS	Contact for details

Quality Control

Our Homochlorocyclizine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet stringent industry standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Individual Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.