Description

2-(2-Chloro-4-Fluorophenoxy)Acetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the phenoxy ring, makes it a critical intermediate for constructing more complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated phenoxy moiety.
• Liquid Crystal Materials: Serves as a starting material for the synthesis of fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Intermediate for creating specialty polymers and resins with enhanced chemical resistance and thermal stability.
• Organic Synthesis Research: A valuable reagent for constructing complex heterocycles and for introducing the 2-chloro-4-fluorophenoxy group into target molecules in academic and industrial R&D.

Basic Information

Product Name	2-(2-Chloro-4-Fluorophenoxy)Acetonitrile
CAS No.	24115-19-3
Molecular Formula	C8H5ClFNO
Molecular Weight	185.58 g/mol
Synonyms	2-(2-Chloro-4-fluorophenoxy)acetonitrile; (2-Chloro-4-fluorophenoxy)acetonitrile; Acetonitrile, (2-chloro-4-fluorophenoxy)-; 2-Chloro-4-fluorophenoxyacetonitrile; Glycolonitrile, 2-(2-chloro-4-fluorophenoxy)-; NSC 403796; 24115-19-3; 2-(2-Chloro-4-fluorophenoxy)ethanenitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Chloro-4-Fluorophenoxy)Acetonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.