Description

D-Alprenolol is a high-purity, non-racemic form of the β-adrenergic receptor antagonist (β-blocker) alprenolol. This compound is of significant value in pharmaceutical research and development, particularly for studying stereoselective drug-receptor interactions and metabolic pathways. It serves as a critical chiral building block and reference standard for analytical method development and quality control in the production of enantiomerically pure active pharmaceutical ingredients (APIs). Researchers and manufacturers in the pharmaceutical and fine chemical sectors require this specific enantiomer for advanced pharmacological studies and the synthesis of targeted therapeutic agents.

Application

• As a chiral reference standard for HPLC and GC method development and validation in pharmaceutical analysis.
• As a key intermediate in the research-scale synthesis of enantiomerically pure β-blocker pharmaceuticals.
• For pharmacological studies investigating the stereoselective binding and activity of β-adrenergic antagonists.
• In metabolic pathway research to understand the enantioselective metabolism of drug compounds.
• As a building block in medicinal chemistry programs focused on cardiovascular drug discovery.
• For use in quality control laboratories to ensure the enantiomeric purity of alprenolol and related substances.

Basic Information

Product Name	D-Alprenolol
CAS No.	23846-72-2
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	(R)-Alprenolol; (R)-1-(2-Allylphenoxy)-3-(isopropylamino)-2-propanol; D-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol; (R)-(-)-Alprenolol; Dextro-Alprenolol; (2R)-1-(2-Allylphenoxy)-3-(propan-2-ylamino)propan-2-ol; Alprenolol Impurity D (Enantiomer); UNII-9M3H5W51AX (component)
EINECS	Contact for details

Quality Control

Our D-Alprenolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC, Area %)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.