Description

9,11-Epoxy-6-Fluoro-17,21-Dihydroxypregn-4-Ene-3,20-Dione-17,21-Diacetate is a high-purity synthetic steroid derivative, primarily valued as a critical pharmaceutical intermediate. Its complex molecular structure, featuring epoxy and fluoro substituents on the pregnane skeleton, makes it a key building block for the synthesis of advanced corticosteroid and progestogen analogs. This compound is essential for research and development laboratories, as well as manufacturing facilities, focused on producing novel therapeutic agents in the steroid hormone class.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent fluorinated corticosteroids and other steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new steroid receptor modulators.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the industrial manufacturing of steroid drugs.
• Biochemical Research: Utilized as a tool compound to study steroidogenesis, enzyme inhibition, and hormonal pathways in experimental settings.

Basic Information

Product Name	9,11-Epoxy-6-Fluoro-17,21-Dihydroxypregn-4-Ene-3,20-Dione-17,21-Diacetate
CAS No.	23641-00-1
Molecular Formula	C₂₅H₃₁FO₇
Molecular Weight	462.51 g/mol
Synonyms	6-Fluoro-9β,11β-epoxy-17α,21-dihydroxypregn-4-ene-3,20-dione 17,21-diacetate; 9β,11β-Epoxy-6α-fluoro-17α,21-dihydroxypregn-4-ene-3,20-dione 17,21-diacetate; 6α-Fluoro-9β,11β-epoxypregna-4-ene-17α,21-diol-3,20-dione 17,21-diacetate; Fluocortolone 17,21-Diacetate 9,11-Epoxide; 9,11-Epoxy-6-fluoroprednisolone 17,21-diacetate; 9β,11β-Epoxy-6α-fluoroprednisolone 17,21-diacetate; Fluocortolone Butyl Epoxide Diacetate (related intermediate)
EINECS	Contact for details

Quality Control

Our 9,11-Epoxy-6-Fluoro-17,21-Dihydroxypregn-4-Ene-3,20-Dione-17,21-Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.