Description

Deterenol Hydrochloride CAS NO 23239-36-3 is a high-purity pharmaceutical intermediate and research chemical of significant importance in medicinal chemistry. Its primary value lies in its role as a key building block for the synthesis of more complex active pharmaceutical ingredients (APIs), particularly those targeting adrenergic systems. This compound is essential for pharmaceutical manufacturers and advanced research institutions engaged in drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of β-adrenergic receptor agonists and related therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for developing new drug candidates in preclinical and clinical research.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate adrenergic pathways and receptor binding.
• Process Chemistry & Scale-up: Employed in optimizing synthetic routes and scaling production from laboratory to pilot plant and commercial manufacturing.
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and quality assurance (QA) laboratories to calibrate instruments and validate analytical methods like HPLC and GC.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized or generic pharmaceuticals.

Basic Information

Product Name	Deterenol Hydrochloride
CAS No.	23239-36-3
Molecular Formula	C12H19NO2 • HCl
Molecular Weight	245.74 g/mol
Synonyms	Deterenol HCl; 1-(3,5-Dihydroxyphenyl)-2-[(1,1-dimethylethyl)amino]ethanol Hydrochloride; (R*,S*)-α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol hydrochloride; Deterenol Hydrochloride; Norfenefrine Impurity; Norfenefrine Related Compound A; tert-Butylnorfenefrine Hydrochloride
EINECS	Contact for details

Quality Control

Our Deterenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.