Description

Bunitrolol Hcl CAS NO 23093-74-5 is a high-purity pharmaceutical intermediate and reference standard belonging to the class of β-adrenergic blocking agents. This compound is critical for research and development in cardiovascular pharmacology, enabling the study of receptor interactions and metabolic pathways. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in drug discovery and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced β-blocker active pharmaceutical ingredients (APIs).
• Reference Standard: Used for quality control, method validation, and calibration in analytical laboratories (HPLC, GC-MS).
• Biochemical Research: Employed in in vitro studies to investigate β-adrenergic receptor binding affinity and selectivity.
• Metabolite Studies: Aids in the identification and quantification of drug metabolites in pharmacokinetic and toxicological research.
• Impurity Profiling: Acts as a known impurity standard to monitor and control the purity of related pharmaceutical compounds.

Basic Information

Product Name	Bunitrolol Hcl
CAS No.	23093-74-5
Molecular Formula	C17H20N2O3 • HCl
Molecular Weight	336.81 g/mol
Synonyms	Bunitrolol Hydrochloride; (±)-Bunitrolol HCl; 2-[3-(tert-Butylamino)-2-hydroxypropoxy]benzonitrile hydrochloride; Koe 1366; Bunitrolol HCl; DL-Bunitrolol hydrochloride; Benzonitrile, 2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our Bunitrolol Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.