Description

11Beta,17-Dihydroxypregna-1,4-Diene-3,20-Dione 11-Nitrate 17-Propionate is a high-purity synthetic steroid derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural modifications, which are critical for exploring novel therapeutic pathways and creating next-generation active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of steroidal drugs, including potential anti-inflammatory and hormonal agents. Consistent quality and reliable supply are paramount for ensuring the integrity of downstream research and production processes.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) research, and metabolic pathway investigations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis (e.g., HPLC, LC-MS).
• Preclinical Studies: Employed in the development and testing of new drug candidates targeting inflammatory or endocrine systems.
• Process Chemistry: Utilized for scaling up synthetic routes and optimizing manufacturing processes for steroid-based therapeutics.

Basic Information

Product Name	11Beta,17-Dihydroxypregna-1,4-Diene-3,20-Dione 11-Nitrate 17-Propionate
CAS No.	23074-99-9
Molecular Formula	C24H31NO7
Molecular Weight	445.51 g/mol
Synonyms	11β,17α-Dihydroxypregna-1,4-diene-3,20-dione 11-nitrate 17-propionate; Prednisolone 11-nitrate 17-propionate; 11-Nitratoprednisolon-17-propionat; 11β-Hydroxy-17α-(1-oxopropoxy)pregna-1,4-diene-3,20-dione 11-nitrate; NSC 113927
EINECS	Contact for details

Quality Control

Our 11Beta,17-Dihydroxypregna-1,4-Diene-3,20-Dione 11-Nitrate 17-Propionate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from advanced techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.