Description

Didesmethyl Chlorpheniramine Maleate Salt is a key pharmaceutical intermediate and active metabolite of the widely used antihistamine, chlorpheniramine. Its primary value lies in enabling advanced research and development into next-generation antihistamine therapies and analytical reference standards. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and analytical service providers focused on allergy, inflammation, and respiratory drug development.

Application

• Pharmaceutical Intermediate: Critical for the synthesis and development of novel antihistamine and anti-allergy drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used as a reference standard and starting material in the study of chlorpheniramine's metabolism and pharmacology.
• Analytical Reference Standard: Serves as a high-purity standard for HPLC, LC-MS, and other chromatographic methods in quality control and bioanalytical studies.
• Metabolite Studies: Essential for pharmacokinetic and pharmacodynamic research to understand drug action, efficacy, and safety profiles.
• Biochemical Research: Used in receptor binding assays and other in-vitro studies to investigate histamine H1-receptor antagonism.

Basic Information

Product Name	Didesmethyl Chlorpheniramine Maleate Salt
CAS No.	23052-94-0
Molecular Formula	C16H19ClN2 • C4H4O4
Molecular Weight	424.87 g/mol
Synonyms	Descarboxy Chlorpheniramine Maleate; Didesmethylchlorpheniramine Maleate; 2-[4-Chlorophenyl(pyridin-2-yl)methoxy]-N,N-dimethylethanamine (Z)-but-2-enedioate; Chlorpheniramine Impurity F (Maleate); Chlorphenamine Didesmethyl Maleate; Chlorpheniramine Didesmethyl Maleate Salt; CP Didesmethyl Maleate
EINECS	Contact for details

Quality Control

Our Didesmethyl Chlorpheniramine Maleate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.