Description

2-Fluoroisophthalonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both fluorine and nitrile functional groups, enables precise molecular design and functionalization. This compound is critically important for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Functional Material Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Chemical Biology Probes: Utilized to synthesize fluorinated probes and tags for studying biological mechanisms and diagnostic applications.

Basic Information

Product Name	2-Fluoroisophthalonitrile
CAS No.	23039-06-7
Molecular Formula	C8H3FN2
Molecular Weight	146.12 g/mol
Synonyms	1,3-Dicyano-2-fluorobenzene; 2-Fluoro-1,3-benzenedicarbonitrile; 2-Fluorobenzene-1,3-dicarbonitrile; Isophthalonitrile, 2-fluoro-; 2-Fluoroisophthalodinitrile; 2-Fluorobenzene-1,3-dinitrile; 2-Fluoroisophthalic acid dinitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoroisophthalonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.