Description

2-Propen-1-One, 1-(4-Fluorophenyl)-3-Phenyl-, (2E)- is a high-purity fluorinated chalcone derivative, a key chemical building block prized for its unique structural motif. This compound is essential for advanced organic synthesis, offering a versatile scaffold for creating novel molecules with targeted properties. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its chalcone structure and fluorine substitution.
• Agrochemical Development: Acts as a key intermediate in the research and development of new pesticides and herbicides, leveraging its bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential electron-transport or emissive layer material in advanced electronic displays and lighting.
• Chemical Biology Probes: Utilized in the design of fluorescent or photoaffinity probes to study biological processes and protein interactions.
• Academic & Industrial R&D: Employed in fundamental organic synthesis research and the development of new catalytic methodologies.

Basic Information

Product Name	2-Propen-1-One, 1-(4-Fluorophenyl)-3-Phenyl-, (2E)-
CAS No.	22966-25-2
Molecular Formula	C15H11FO
Molecular Weight	226.25 g/mol
Synonyms	(E)-1-(4-Fluorophenyl)-3-phenylprop-2-en-1-one; (E)-3-(4-Fluorophenyl)-1-phenyl-2-propen-1-one; 4'-Fluorochalcone; (E)-4-Fluorochalcone; 1-(4-Fluorophenyl)-3-phenyl-2-propen-1-one; trans-4-Fluorochalcone; NSC 403914; 2-Propen-1-one, 1-(4-fluorophenyl)-3-phenyl-, (E)-
EINECS	Contact for details

Quality Control

Our 2-Propen-1-One, 1-(4-Fluorophenyl)-3-Phenyl-, (2E)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	85 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.