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(11Beta)-11,17-Dihydroxy-16-Methylene-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride CAS NO 22887-42-9


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CAS No.:22887-42-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(11Beta)-11,17-Dihydroxy-16-Methylene-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride is a high-purity synthetic steroid derivative, primarily valued as a critical pharmaceutical intermediate. Its precise chemical structure is essential for the development and production of advanced corticosteroid-based therapeutics. This compound is specifically required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel anti-inflammatory and immunosuppressive agents.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of potent corticosteroid drugs.
  • Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new steroid-based therapies.
  • Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthesis processes for final drug substances.
  • Biochemical Research: Utilized as a reference standard or probe in studying glucocorticoid receptor interactions and metabolic pathways.

Basic Information

Item Details
Product Name (11Beta)-11,17-Dihydroxy-16-Methylene-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride
CAS No. 22887-42-9
Molecular Formula C₂₈H₄₀ClNO₆
Molecular Weight 522.08 g/mol
Synonyms 16-Methylene Prednisolone 21-Diethylaminoacetate Hydrochloride; 16-Methyleneprednisolone Diethylaminoacetate HCl; (11β)-11,17-Dihydroxy-16-methylen-3,20-dioxopregna-1,4-dien-21-yl N,N-diethylaminoacetat Hydrochlorid; 21-(Diethylamino)acetate 16-methyleneprednisolone hydrochloride; Prednisolone 16-Methylene 21-Diethylaminoacetate Hydrochloride; 16-Methylene Prednisolone Diethylaminoacetate Hydrochloride Salt; 21-(N,N-Diethylglycyl)oxy-16-methyleneprednisolone hydrochloride
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Quality Control

Our (11Beta)-11,17-Dihydroxy-16-Methylene-3,20-Dioxopregna-1,4-Dien-21-Yl N,n-Diethylaminoacetate Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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