Description

Desmethyl Chlorpheniramine Maleate Salt is a high-purity pharmaceutical intermediate and active metabolite of the widely used antihistamine, chlorpheniramine. This compound is critical for research and development in pharmacology and for the synthesis of advanced therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and analytical service providers focused on allergy, respiratory, and central nervous system drug development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antihistamine and antiallergic drug candidates.
• Metabolite Reference Standard: Essential for bioanalytical method development, pharmacokinetic studies, and drug metabolism research related to chlorpheniramine.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new formulations or evaluating drug efficacy and safety profiles.
• Quality Control & Analytical Testing: Serves as a certified reference material (CRM) in HPLC, LC-MS, and other chromatographic assays for impurity profiling and assay validation.
• Biochemical Research: Tool compound for studying histamine H1 receptor interactions and related neurological pathways.

Basic Information

Product Name	Desmethyl Chlorpheniramine Maleate Salt
CAS No.	22630-25-7
Molecular Formula	C19H21ClN2O4
Molecular Weight	376.84 g/mol
Synonyms	Descarboxychlorpheniramine Maleate; 2-[4-Chlorophenyl(pyridin-2-yl)methoxy]-N,N-dimethylethanamine Maleate; Monodesmethylchlorpheniramine Maleate; Chlorpheniramine Metabolite Maleate; Didesmethylchlorpheniramine Maleate (Note: Verify specific isomer); 4-Chloro-α-(2-dimethylaminoethyl)-α-methyl-2-pyridineethanol Maleate (1:1); (RS)-2-[p-Chloro-α-(2-dimethylaminoethyl)benzyl]pyridine Maleate Salt
EINECS	Contact for details

Quality Control

Our Desmethyl Chlorpheniramine Maleate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets stringent standards for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.