Description

Phosphonic Difluoride, (Pentafluorophenyl)- is a specialized organofluorine compound that serves as a key building block in advanced chemical synthesis. This high-value reagent is critical for introducing the pentafluorophenylphosphonic difluoride moiety into target molecules, enabling the development of novel materials and active compounds. It is primarily sought by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated phosphonate groups for enhanced metabolic stability or binding affinity.
• Agrochemical Research: Serves as a precursor for developing novel herbicides, pesticides, and plant growth regulators with improved efficacy and environmental profiles.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized fluorinated phosphine ligands used in homogeneous catalysis and cross-coupling reactions.
• Material Science: A key monomer or modifier in the production of fluorinated polymers and advanced materials with unique surface properties, thermal stability, or chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing phosphorus(V) centers and pentafluorophenyl groups into complex organic frameworks in medicinal and process chemistry.

Basic Information

Product Name	Phosphonic Difluoride, (Pentafluorophenyl)-
CAS No.	22474-68-6
Molecular Formula	C6HF7O2P
Molecular Weight	248.04 g/mol
Synonyms	Pentafluorophenylphosphonic Difluoride; (Pentafluorophenyl)phosphonic Difluoride; Difluoro(pentafluorophenyl)phosphine Oxide; Pentafluorophenylphosphonyl Difluoride; C6F5P(O)F2; (Perfluorophenyl)phosphonic Difluoride
EINECS	Contact for details

Quality Control

Every batch of Phosphonic Difluoride, (Pentafluorophenyl)- is produced and analyzed under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (NMR)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.