Description

Betamethasone Benzoate (200 Mg) is a potent synthetic corticosteroid ester, widely recognized for its anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of formulated dermatological and topical products. It is primarily required by pharmaceutical manufacturers and compounding pharmacies for the production of creams, ointments, and lotions designed to treat severe skin conditions such as eczema, psoriasis, and dermatitis. Consistent quality and reliable supply are paramount for maintaining product integrity in these sensitive applications.

Application

• Primary API in the formulation of topical corticosteroid creams and ointments.
• Key ingredient for dermatological preparations targeting inflammatory skin disorders like eczema and psoriasis.
• Used in compounding pharmacies for customized topical medication.
• Component in veterinary medicinal products for treating skin inflammation in animals.
• Utilized in clinical research and development of new anti-inflammatory therapies.
• Applied in the manufacture of medicated tapes and patches for localized delivery.

Basic Information

Product Name	Betamethasone Benzoate (200 Mg)
CAS No.	22298-29-9
Molecular Formula	C28H35FO6
Molecular Weight	486.58 g/mol
Synonyms	9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-benzoate; Betamethasone 17-benzoate; Benzoic acid, (11β,16β)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17-ester; U-67590A; Betnovate (as component); Celestoderm-V (as component)
EINECS	244-879-7

Quality Control

Our Betamethasone Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, with typical purity exceeding 98.5%. Testing includes identification, assay, and control of specific impurities and residual solvents. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities NMT 1.5% Any individual impurity NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	+103° to +111° (c=1 in dioxane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.