Description

2-Fluoro-17-Ethynylestradiol is a fluorinated derivative of the synthetic estrogen, 17α-ethynylestradiol, designed for advanced research and development applications. This compound is valued for its modified biological activity and stability, making it a critical intermediate in the synthesis of novel pharmaceutical agents and biochemical probes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor binding affinity and metabolic pathways.
• Drug Discovery: Serves as a precursor in the development of targeted therapies for endocrine-related conditions.
• Academic Research: Employed in university and institutional labs for chemical and pharmacological studies on fluorinated steroids.
• Reference Material: Utilized in analytical laboratories for method development and quality control testing of related compounds.

Basic Information

Product Name	2-Fluoro-17-Ethynylestradiol
CAS No.	22165-49-7
Molecular Formula	C₂₀H₂₃FO₂
Molecular Weight	314.40 g/mol
Synonyms	2-Fluoro-17α-ethynylestradiol; 2-Fluoro-EE2; 17α-Ethynyl-2-fluoroestra-1,3,5(10)-triene-3,17β-diol; 2-Fluoro-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol; 2-F-EE2; 2-Fluoroethynylestradiol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-17-Ethynylestradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.