Description

Alanine, 2-Cyano-N,n-Difluoro-, Methyl Ester (8Ci) is a specialized fluorinated amino acid derivative, identified by CAS NO 22058-18-0, that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both cyano and difluoroamino groups, makes it a valuable precursor for introducing fluorine and nitrogen-containing functionalities into target molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Peptide Mimetics Research: Employed in the synthesis of modified peptides and peptidomimetics to study structure-activity relationships and improve metabolic stability.
• Fluorine Chemistry Building Block: Serves as a versatile reagent for introducing the difluoroamino (N(F)₂) group into complex organic frameworks in academic and industrial R&D settings.
• Material Science Precursor: Investigated for the synthesis of specialized polymers and functional materials that require fluorinated amino acid components.

Basic Information

Product Name	Alanine, 2-Cyano-N,n-Difluoro-, Methyl Ester (8Ci)
CAS No.	22058-18-0
Molecular Formula	C₅H₆F₂N₂O₂
Molecular Weight	164.11 g/mol
Synonyms	2-Cyano-N,N-difluoroalanine methyl ester; Methyl 2-cyano-2-(difluoroamino)propanoate; Methyl 2-cyano-N,N-difluoroalaninate; Alanine, 2-cyano-N,N-difluoro-, methyl ester; Difluoroamino cyano alanine methyl ester; NSC 339063; 2-(Difluoroamino)-2-cyanopropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Alanine, 2-Cyano-N,n-Difluoro-, Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For custom synthesis or specific grade requirements, our technical team is available to discuss tailored quality specifications to meet your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.