Description

1-Acetyl-5-Hydroxy-17-Methoxy-20,21-Dinoraspidospermidine is a complex, high-purity alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological reference standard and a sophisticated building block for the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and neuropharmacology studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid-based drug candidates targeting neurological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing (HPLC, LC-MS).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize biological activity.
• Biochemical Tool Compound: Utilized in in-vitro and ex-vivo studies to investigate specific receptor interactions and enzyme inhibition.
• Academic Synthesis Projects: Serves as a challenging target molecule or starting material for advanced organic chemistry research and methodology development.

Basic Information

Product Name	1-Acetyl-5-Hydroxy-17-Methoxy-20,21-Dinoraspidospermidine
CAS No.	21451-69-4
Molecular Formula	C22H30N2O3
Molecular Weight	370.49 g/mol
Synonyms	1-Acetyl-5-hydroxy-17-methoxy-20,21-dinoraspidospermidine; 20,21-Dinoraspidospermidine-1-acetyl-5-hydroxy-17-methoxy derivative; Aspidospermidine derivative; (19S)-1-Acetyl-19-ethyl-5-hydroxy-17-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine; Contact for additional IUPAC names and research codes.
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Hydroxy-17-Methoxy-20,21-Dinoraspidospermidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (IR, NMR), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.