Description

Tralonide CAS NO 21365-49-1 is a synthetic corticosteroid compound known for its potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for the development and formulation of advanced topical and systemic pharmaceutical products. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of treatments for dermatological conditions, allergic reactions, and other inflammatory disorders.

Application

• Pharmaceutical API: Core ingredient in the formulation of topical creams, ointments, and lotions for treating eczema, psoriasis, and dermatitis.
• Veterinary Medicine: Used in anti-inflammatory preparations for skin conditions in animals.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and new drug development.
• Advanced Drug Delivery Systems: Incorporated into controlled-release formulations and transdermal patches.
• Ophthalmic Preparations: Component in eye drops and ointments for treating ocular inflammation.
• Analytical Reference: Used as a certified reference material (CRM) in quality control laboratories for HPLC and other analytical methods.

Basic Information

Product Name	Tralonide
CAS No.	21365-49-1
Molecular Formula	C₂₄H₃₁FO₆
Molecular Weight	434.50 g/mol
Synonyms	9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Fluocinolone Acetonide (related isomer); RS-2252; SQ-15101; Tralonidum; Fluocinolone Acetonide Analog; Corticosteroid RS-2252
EINECS	Contact for details

Quality Control

Our Tralonide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification (IR, HPLC), assay, and impurity profiling to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) are provided with every shipment, confirming compliance with relevant internal specifications and supporting cGMP (current Good Manufacturing Practice) requirements for API production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.