Description

(1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,4α,7,10,12-Pentahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester is a complex, high-purity tetracycline derivative with significant pharmaceutical relevance. This compound is valued for its role as a critical intermediate in the synthesis of advanced antibiotics and other bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel tetracycline-class antibiotics and other therapeutic agents.
• Biochemical Research: Used as a reference standard and precursor in studies of antibiotic mechanisms of action and bacterial resistance.
• Medicinal Chemistry: Serves as a core scaffold for the development of new chemical entities with potential antibacterial, anti-inflammatory, or anticancer properties.
• Process Development: Employed in the scale-up and optimization of synthetic routes for complex pharmaceutical actives.
• Analytical Standard: Utilized for method development, validation, and quality control testing in analytical laboratories.

Basic Information

Product Name	(1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,4α,7,10,12-Pentahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester
CAS No.	21204-34-2
Molecular Formula	C₂₄H₂₆O₁₀
Molecular Weight	474.46 g/mol
Synonyms	Methyl (1R,2S,4S,4aS,5aS,6S,12aS)-2-Ethyl-1,2,3,4,4a,5,5a,6,11,12a-decahydro-4,6,10,11,12-pentahydroxy-4a,6,11-trioxo-1-naphthacenecarboxylate; 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline Methyl Ester; Anhydrotetracycline Methyl Ester Derivative; ATC Methyl Ester; Tetracycline Derivative Intermediate
EINECS	Contact for details

Quality Control

Our (1R)-2-Ethyl-1,2,3,4,6,11-Hexahydro-2α,4α,7,10,12-Pentahydroxy-6,11-Dioxo-1β-Naphthacenecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.