Description

Daunorubicin is a potent anthracycline antibiotic and antineoplastic agent derived from *Streptomyces peucetius*. It is a critical chemotherapeutic compound that functions by intercalating into DNA and inhibiting topoisomerase II, leading to the disruption of DNA replication and synthesis in rapidly dividing cells. This product is essential for pharmaceutical manufacturers, research institutions, and clinical laboratories engaged in the development and production of oncology therapeutics, particularly for the treatment of acute leukemias.

Application

• Oncological Pharmaceutical Manufacturing: A key active pharmaceutical ingredient (API) in the formulation of injectable chemotherapy drugs for treating acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).
• Biomedical Research: Used as a reference standard and experimental compound in cancer biology studies to investigate mechanisms of apoptosis, DNA damage, and drug resistance.
• Drug Discovery & Development: Serves as a lead compound or a benchmark in the synthesis and screening of novel anthracycline derivatives and combination therapies.
• Clinical Diagnostics: Employed in laboratory settings for quality control testing and assay calibration of daunorubicin-based medications.
• Veterinary Oncology: Applied in the development of chemotherapeutic treatments for certain cancers in animals.

Basic Information

Product Name	Daunorubicin
CAS No.	20830-81-3
Molecular Formula	C27H29NO10
Molecular Weight	527.52 g/mol
Synonyms	Daunomycin; Rubidomycin; Cerubidine; Daunoblastin; (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-; Antibiotic FI 1762; NSC 82151
EINECS	244-069-7

Quality Control

Our Daunorubicin is manufactured and tested under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Specifications are aligned with pharmacopeial guidelines. A detailed Certificate of Analysis (COA), including results for identity, purity, and related substances, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange-red to red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.