Description

2-Trifluoroacetamido-7-Nitrofluorene is a specialized fluorinated nitrofluorene derivative, a high-value building block in advanced organic synthesis. Its unique structure, combining electron-withdrawing nitro and trifluoroacetamido groups on a rigid fluorene scaffold, makes it a critical intermediate for developing novel materials and pharmaceuticals. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating complex molecules with tailored electronic and photophysical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, pesticides, and fungicides where the fluorene core and nitro group contribute to biological activity.
• Organic Electronic Materials: Acts as a building block for electron-transport materials, non-linear optical (NLO) chromophores, and other advanced organic semiconductors due to its electron-deficient aromatic system.
• Dye and Pigment Synthesis: Employed in the creation of specialized nitro- and amino-fluorene based dyes with specific color and light-fastness properties.
• Ligand and Catalyst Development: Utilized to synthesize complex, polycyclic ligands for catalysis or metal-organic frameworks (MOFs).
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	2-Trifluoroacetamido-7-Nitrofluorene
CAS No.	2926-70-7
Molecular Formula	C₁₇H₉F₃N₂O₃
Molecular Weight	346.26 g/mol
Synonyms	7-Nitro-2-(trifluoroacetamido)fluorene; 2-Trifluoroacetamido-7-nitro-9H-fluorene; N-(7-Nitro-9H-fluoren-2-yl)-2,2,2-trifluoroacetamide; 2-Amino-7-nitrofluorene trifluoroacetamide derivative; 2926-70-7; 2-TFA-7-NF
EINECS	Contact for details

Quality Control

Every batch of 2-Trifluoroacetamido-7-Nitrofluorene is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.