Description

20-Dihydroprednisone is a synthetic corticosteroid derivative and a key pharmaceutical intermediate. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and for research into anti-inflammatory mechanisms. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in steroid chemistry and drug development. The product is supplied with a focus on high purity and consistency to meet stringent R&D and production requirements.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent corticosteroid APIs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related steroid products.
• Biochemical Research: Serves as a tool compound for studying glucocorticoid receptor interactions and metabolic pathways in preclinical models.
• Process Development: Employed in scaling up and optimizing manufacturing routes for steroid-based therapeutics.
• Custom Synthesis: A starting material for the preparation of novel steroid analogs with potential therapeutic applications.

Basic Information

Product Name	20-Dihydroprednisone
CAS No.	2899-94-7
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	20-Dihydro-17α,21-dihydroxypregn-4-ene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione; 20-Dihydro-17α,21-dihydroxy-1,4-pregnadiene-3,11-dione
EINECS	Contact for details

Quality Control

Our 20-Dihydroprednisone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.