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2-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenol Hydrochloride CAS NO 2829-92-7
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CAS No.:2829-92-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenol Hydrochloride is a high-purity chemical intermediate and active pharmaceutical ingredient (API) of significant commercial and research interest. Its core value lies in its role as a key synthetic precursor for β-adrenergic blocking agents, commonly known as β-blockers, which are critical in cardiovascular medicine. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis facilities focused on developing and producing therapeutic agents for hypertension, angina, and arrhythmia.
Application
- Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of β-blocker drugs like Oxprenolol and related compounds.
- Active Pharmaceutical Ingredient (API): Serves as the active moiety in certain formulated cardiovascular medications.
- Biochemical Research: Used in pharmacological studies to investigate adrenergic receptor mechanisms and drug interactions.
- Fine Chemical Synthesis: Employed in custom synthesis and process development for novel therapeutic molecules targeting the sympathetic nervous system.
- Reference Standard: Utilized as an analytical standard in quality control laboratories for drug testing and method validation.
Basic Information
| Product Name | 2-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenol Hydrochloride |
| CAS No. | 2829-92-7 |
| Molecular Formula | C12H20ClNO3 |
| Molecular Weight | 261.75 g/mol |
| Synonyms | Oxprenolol Hydrochloride Impurity; 1-(2-Allyloxyphenoxy)-3-(isopropylamino)-2-propanol Hydrochloride; 2-[2-Hydroxy-3-(isopropylamino)propoxy]phenol Hydrochloride; 3-Isopropylamino-1-(o-allyloxyphenoxy)-2-propanol Hydrochloride; 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol Hydrochloride; Allyloxyphenoxypropanolamine Hydrochloride; Isopropylamino-propoxyphenol HCl |
| EINECS | 220-600-7 |
Quality Control
Our 2-[2-Hydroxy-3-[(1-Methylethyl)Amino]Propoxy]Phenol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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