Description

α-D-Mannopyranosyl Fluoride is a specialized fluorinated carbohydrate derivative, serving as a crucial glycosyl donor and synthetic intermediate in organic chemistry. Its primary value lies in enabling the stereoselective construction of complex oligosaccharides and glycoconjugates, which are fundamental to biological research and pharmaceutical development. This compound is essential for researchers and manufacturers in the fields of glycobiology, medicinal chemistry, and carbohydrate synthesis, where precise control over glycosidic bond formation is required.

Application

• Glycosylation Reactions: Acts as a key mannosyl donor for the stereoselective synthesis of α-linked mannose-containing oligosaccharides and glycans.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically active glycoconjugates for drug discovery and biological studies.
• Enzyme Substrate/Inhibitor Studies: Serves as a substrate or inhibitor for glycosidases and glycosyltransferases to study enzyme mechanisms and develop therapeutic agents.
• Probe Development: Utilized in the creation of fluorescent or affinity-labeled carbohydrate probes for imaging and detecting biological targets.
• Pharmaceutical Intermediates: A critical building block in the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and vaccine components.
• Material Science: Applied in the surface functionalization of materials with carbohydrate motifs for biosensing and biocompatibility applications.

Basic Information

Product Name	α-D-Mannopyranosyl Fluoride
CAS No.	2713-54-4
Molecular Formula	C6H11FO5
Molecular Weight	182.15 g/mol
Synonyms	α-D-Mannopyranosyl fluoride; 1-Fluoro-α-D-mannopyranose; α-D-Mannosyl fluoride; Fluorine α-D-mannopyranoside; 1-Fluoro-α-D-mannose; α-D-Mannose fluoride; α-D-Mannofuranosyl fluoride (common misnomer); 1-Deoxy-1-fluoro-α-D-mannopyranose
EINECS	Contact for details

Quality Control

Our α-D-Mannopyranosyl Fluoride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation analysis, to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.