Description

1,4-Dichloro-2-Fluoro-5-Nitro-Benzene is a high-purity halogenated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including antibacterial and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Material Science: Serves as a monomer or building block for synthesizing specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: An intermediate in the production of complex, high-performance organic dyes and pigments.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring novel fluorination reactions and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	1,4-Dichloro-2-Fluoro-5-Nitro-Benzene
CAS No.	2624-66-0
Molecular Formula	C6H2Cl2FNO2
Molecular Weight	209.99 g/mol
Synonyms	2-Fluoro-1,4-dichloro-5-nitrobenzene; 1,4-Dichloro-2-fluoro-5-nitrobenzene; 5-Nitro-1,4-dichloro-2-fluorobenzene; 2,5-Dichloro-4-fluoronitrobenzene; Benzene, 1,4-dichloro-2-fluoro-5-nitro-; 4-Fluoro-3,6-dichloronitrobenzene; 2624-66-0; DCFNB
EINECS	220-087-7

Quality Control

Our 1,4-Dichloro-2-Fluoro-5-Nitro-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.