Description

Actinomycin Vi CAS NO 2612-14-8 is a potent polypeptide antibiotic belonging to the actinomycin family, characterized by its chromophore-peptide structure. This compound is valued for its ability to intercalate into DNA, inhibiting transcription, which makes it a critical tool in biochemical research and a reference standard in analytical laboratories. It is primarily sought after by researchers in oncology, molecular biology, and by manufacturers in the pharmaceutical sector for quality control and development purposes.

Application

• Biochemical Research: Used as a potent inhibitor of RNA synthesis to study transcription mechanisms and gene expression.
• Oncology Research: Serves as a reference compound in studies investigating DNA-binding agents and their cytotoxic effects on cancer cell lines.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for quality control (QC) and quality assurance (QA) in drug manufacturing and regulatory testing.
• Microbiological Studies: Applied in research to understand its antibiotic properties and mechanisms of action against various microorganisms.
• Molecular Biology Reagent: Utilized in laboratory experiments to selectively block transcriptional activity.

Basic Information

Product Name	Actinomycin Vi
CAS No.	2612-14-8
Molecular Formula	C62H86N12O16
Molecular Weight	1255.42 g/mol
Synonyms	Actinomycin VI; Actinomycin C3; Actinomycin D analog; Sanamycin VI; Dactinomycin derivative; NSC 83688; Antibiotic 2612-14-8; 2-Amino-N, N'-bis[(6S,9S,18S)-6,9,18-tris(2-amino-2-oxoethyl)-15-benzyl-4,7,10,13,16-pentaoxo-3,17-dioxa-5,8,11,14-tetraazaoctadec-1-yl]-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
EINECS	Contact for details

Quality Control

Our Actinomycin Vi is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in DMSO, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.