Description

9-Fluoro-11Beta,16Alpha,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate) is a high-purity synthetic corticosteroid derivative, specifically the 21-hemisuccinate ester of a fluorinated pregnadiene. This compound is a critical pharmaceutical intermediate valued for its potent anti-inflammatory and immunosuppressive activity. It is primarily required by research institutions and pharmaceutical manufacturers for the development and production of advanced topical and injectable corticosteroid formulations.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of potent topical corticosteroids.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for creating novel steroid-based therapeutics with enhanced efficacy and reduced side effects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory compliance in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating glucocorticoid receptor interactions, anti-inflammatory pathways, and metabolic effects.
• Veterinary Medicine: Potential use in developing anti-inflammatory treatments for animals.

Basic Information

Product Name	9-Fluoro-11Beta,16Alpha,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate)
CAS No.	2561-01-5
Molecular Formula	C₂₅H₃₁FO₈
Molecular Weight	478.51 g/mol
Synonyms	Fluocinolone Acetonide 21-Acetate (related ester); 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-hemisuccinate; Fluocinolone Acetonide Hemisuccinate; Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, 21-(hydrogen succinate); 21-Hemisuccinyloxy-9α-fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,16Alpha,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.