Description

Antazoline Hydrochloride is a high-purity pharmaceutical-grade compound, essential for its potent antihistaminic and anticholinergic properties. This active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of ophthalmic and topical formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for allergic conjunctivitis and related conditions. Our supply guarantees consistent quality and reliable availability for global production needs.

Application

• Ophthalmic Solutions: Primary active ingredient in eye drops for the symptomatic relief of allergic conjunctivitis and other ocular allergies.
• Topical Preparations: Used in creams and ointments for managing skin allergies and inflammatory dermatological conditions.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the production of more complex antihistamine drugs.
• Biochemical Research: Utilized in laboratory studies to investigate histamine H1-receptor antagonism and related pharmacological pathways.
• Veterinary Medicine: Applied in formulations for treating allergic reactions in animals.
• Reference Standard: Sourced by analytical laboratories for use as a high-purity standard in quality control and method validation (HPLC, GC).

Basic Information

Product Name	Antazoline Hydrochloride
CAS No.	2508-72-7
Molecular Formula	C17H19N3·HCl
Molecular Weight	301.81 g/mol
Synonyms	Antazoline HCl; 2-[(N-Benzylanilino)methyl]-2-imidazoline hydrochloride; Phenazoline Hydrochloride; Antasten; Antistin; Azalone; Histostab; Imidamin Hydrochloride; N-(Benzylphenylaminomethyl)imidazoline Hydrochloride
EINECS	219-730-8

Quality Control

Our Antazoline Hydrochloride is manufactured under strict quality management systems. Each batch is tested to meet stringent specifications for identity, purity, and impurity profiles, ensuring compliance with pharmaceutical standards. Comprehensive testing includes HPLC for assay and related substances, residual solvent analysis, and microbiological examination. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%
Microbial Limits	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.