Description

Pregna-1,4-Diene-3,20-Dione,17-Hydroxy- CAS NO 2477-61-4 is a high-purity steroid derivative, also known as 17-Hydroxyprednisolone, serving as a critical pharmaceutical intermediate. Its value lies in its role as a versatile precursor for synthesizing advanced corticosteroid APIs, ensuring downstream manufacturing efficiency and quality. This compound is essential for R&D and production facilities in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potent corticosteroid active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for developing novel anti-inflammatory and immunosuppressive drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex steroid-based molecules for various therapeutic applications.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione,17-Hydroxy-
CAS No.	2477-61-4
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	17-Hydroxyprednisolone; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione; 17α-Hydroxyprednisolone; δ1-Cortisol; 1,2-Dehydrocortisol; NSC 10483; 17-Hydroxy-1,4-pregnadiene-3,20-dione
EINECS	219-617-5

Quality Control

Our Pregna-1,4-Diene-3,20-Dione,17-Hydroxy- is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical R&D and intermediate use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.