Description

Perfluoro-tert-Butanol is a highly fluorinated tertiary alcohol characterized by its strong acidity and volatility. This unique structure makes it a valuable fluorinated building block and a potent acid catalyst in specialized organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors. Its properties are critical for developing compounds with enhanced stability, bioavailability, or specific surface characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key fluorinated synthon for introducing the perfluoro-tert-butyl group into drug candidates to modulate lipophilicity and metabolic stability.
• Catalyst & Reagent: Acts as a strong, volatile acid catalyst in esterification, etherification, and other acid-promoted organic reactions, often used where easy removal is required.
• Surface Modification Agent: Used to impart highly hydrophobic and oleophobic properties to polymers, coatings, and materials via chemical grafting.
• Agrochemical Synthesis: Employed in the research and production of fluorinated pesticides and herbicides to enhance their environmental persistence and efficacy.
• Ligand & Complexation Studies: Utilized in coordination chemistry due to its strong electron-withdrawing perfluoroalkyl group, influencing metal-ligand interactions.
• Analytical Chemistry: Can be used as a derivatization agent or a volatile standard in gas chromatography (GC) and mass spectrometry (MS) applications.

Basic Information

Product Name	Perfluoro-tert-Butanol
CAS No.	2378-02-1
Molecular Formula	C4H3F9O
Molecular Weight	238.05 g/mol
Synonyms	1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propan-2-ol; (CF3)3COH; Nonafluoro-tert-butyl alcohol; Perfluoro(2-methyl-2-propanol); Tris(trifluoromethyl)methanol; PFTB; Heptafluoro-2-(trifluoromethyl)propan-2-ol; Perfluoro-tert-butanol
EINECS	219-154-7

Quality Control

Our Perfluoro-tert-Butanol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (by GC/HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are securely sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.290 - 1.300
Density (20°C)	1.65 - 1.75 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.