Description

2,4,5,6-Tetrafluoroisophthalonitrile is a high-value, multi-fluorinated aromatic nitrile building block essential for advanced material synthesis. Its unique structure, featuring four fluorine atoms and two cyano groups on a benzene ring, makes it a critical precursor for creating polymers and small molecules with exceptional thermal stability, chemical resistance, and specific electronic properties. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a fundamental building block for fluorine-containing liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved performance and durability.
• High-Performance Polymers: A monomer for synthesizing polyimides, polyamides, and other engineering plastics with enhanced thermal stability, low dielectric constant, and chemical resistance for electronics and aerospace applications.
• Metal-Organic Framework (MOF) Linker: Employed in the construction of fluorinated MOFs for specialized gas separation, storage, and catalysis due to its rigid, multi-dentate structure.
• Fluorinated Dye & Pigment Intermediate: Used to synthesize specialty dyes and pigments with unique color fastness and solubility properties.

Basic Information

Product Name	2,4,5,6-Tetrafluoroisophthalonitrile
CAS No.	2377-81-3
Molecular Formula	C8F4N2
Molecular Weight	200.09 g/mol
Synonyms	1,3-Dicyano-2,4,5,6-tetrafluorobenzene; Tetrafluoroisophthalonitrile; 2,4,5,6-Tetrafluorobenzene-1,3-dicarbonitrile; Isophthalonitrile, 2,4,5,6-tetrafluoro-; Benzene-1,3-dicarbonitrile, 2,4,5,6-tetrafluoro-; TFIPN; 2377-81-3 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2,4,5,6-Tetrafluoroisophthalonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.