Description

2-Chloro-6-(Trifluoromethyl)Be CAS NO 2376-00-3 is a versatile halogenated aromatic building block characterized by its chloro and trifluoromethyl substituents. This compound is a critical intermediate in advanced organic synthesis, valued for its ability to introduce both halogen and fluorine-containing functional groups into target molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials that require specific halogenated aromatic units.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, functionalized aromatic systems.
• Fluorine Chemistry: An important reagent for introducing fluorine atoms into organic molecules, a common strategy in drug design to modulate metabolism, bioavailability, and binding affinity.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Be CAS NO 2376-00-3
CAS No.	2376-00-3
Molecular Formula	C7H4ClF3
Molecular Weight	180.56 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-o-xylene; 1-Chloro-2-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluorotoluene; o-Chlorobenzotrifluoride; 2-Chlorobenzyltrifluoride; 2-Chloro-α,α,α-trifluoromethylbenzene; (2-Chlorophenyl)trifluoromethane; Benzene, 1-chloro-2-(trifluoromethyl)-
EINECS	219-155-7

Quality Control

Our production of 2-Chloro-6-(Trifluoromethyl)Be CAS NO 2376-00-3 adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Density	1.35 - 1.40 g/cm³ @ 20°C
Boiling Point	Approx. 165-170°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.