Description

6Beta-Fluoro-3Beta,5Alpha,17,21-Tetrahydroxy-16Alpha-Methylpregnan-20-One 21-Acetate is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise fluorinated and hydroxylated structure provides a versatile scaffold for the development of potent corticosteroid and other steroidal APIs. This compound is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors requiring reliable, high-quality building blocks for complex molecule production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent fluorinated corticosteroids and other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting inflammation and hormonal pathways.
• Process Chemistry: Serves as a critical starting material or intermediate in multi-step GMP synthesis for commercial-scale pharmaceutical manufacturing.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Fine Chemical Synthesis: Utilized in the production of specialized steroidal compounds for various research and industrial applications.

Basic Information

Product Name	6Beta-Fluoro-3Beta,5Alpha,17,21-Tetrahydroxy-16Alpha-Methylpregnan-20-One 21-Acetate
CAS No.	2353-58-4
Molecular Formula	C24H37FO6
Molecular Weight	440.55 g/mol
Synonyms	6β-Fluoro-3β,5α,17,21-Tetrahydroxy-16α-Methylpregnan-20-One 21-Acetate; 6β-Fluoro-16α-Methylprednisolone 21-Acetate; 6β-Fluoro-16α-Methyl-11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-Acetate (related structure); 6-Fluoro-16α-Methylprednisolone Acetate; 2353-58-4; 6β-Fluoro-16α-methylprednisolone 21-acetate; 6β-Fluoro-16α-methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our 6Beta-Fluoro-3Beta,5Alpha,17,21-Tetrahydroxy-16Alpha-Methylpregnan-20-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards suitable for pharmaceutical R&D and intermediate use. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.