Description

p-Toluenesulfonic Acid 2,2-Dimethylpropyl Ester is a specialized organic sulfonate ester, a valuable intermediate and reagent in advanced chemical synthesis. Its structure offers unique reactivity, making it a critical component for introducing the p-toluenesulfonyl (tosyl) protecting group and for use as an alkylating agent in controlled reactions. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups or as an alkylating agent in multi-step syntheses.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its ester functionality is leveraged for specific molecular modifications.
• Polymer Chemistry: Acts as a monomer or chain transfer agent in the production of specialized polymers and resins, influencing polymer properties and molecular weight.
• Organic Synthesis Reagent: A versatile tool in research laboratories for tosylation reactions, protecting hydroxyl groups to control regioselectivity in complex organic transformations.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals where sulfonate esters are required for specific solubility or reactivity profiles.
• Cross-Coupling Reactions: Can be utilized as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.

Basic Information

Product Name	p-Toluenesulfonic Acid 2,2-Dimethylpropyl Ester
CAS No.	2346-07-8
Molecular Formula	C12H18O3S
Molecular Weight	242.34 g/mol
Synonyms	Neopentyl p-toluenesulfonate; 2,2-Dimethylpropyl 4-methylbenzenesulfonate; p-Toluenesulfonic acid neopentyl ester; Tosic acid neopentyl ester; Neopentyl tosylate; 4-Methylbenzenesulfonic acid 2,2-dimethylpropyl ester; 1,1-Dimethylpropyl p-toluenesulfonate
EINECS	219-068-7

Quality Control

Our p-Toluenesulfonic Acid 2,2-Dimethylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.