Description

3,5-Difluoronitrobenzene is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and fluorine substituents, makes it a critical building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated aromatic rings.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoro-nitrobenzene moiety imparts specific biological activity.
• Liquid Crystal Materials: Serves as a starting material for the synthesis of fluorinated liquid crystal compounds used in display technologies.
• Functional Polymer Monomers: Employed in the creation of specialty polymers with enhanced chemical resistance or specific electronic properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce functionalized aromatic systems.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of specialized dyes and pigments.

Basic Information

Product Name	3,5-Difluoronitrobenzene
CAS No.	2265-94-3
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	1,3-Difluoro-5-nitrobenzene; 3,5-Difluoro-1-nitrobenzene; m-Difluoronitrobenzene; Nitro-3,5-difluorobenzene; Benzene, 1,3-difluoro-5-nitro-; 5-Nitro-1,3-difluorobenzene
EINECS	218-873-8

Quality Control

Our 3,5-Difluoronitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.