Description

(-)-Trimeprazine CAS NO 2256-27-1 is the levorotatory enantiomer of the phenothiazine derivative trimeprazine, a compound of significant interest in pharmaceutical research and development. This specific stereoisomer is valued for its precise biological activity and serves as a critical chiral building block and reference standard. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), method development, and pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of enantiomerically pure therapeutic agents.
• Reference Standard: Used in analytical laboratories for method validation, quality control, and regulatory compliance testing.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding affinity and stereospecific activity.
• Fine Chemical Synthesis: Acts as a specialized building block for creating novel chemical entities in medicinal chemistry.
• Academic Research: Utilized in universities and research institutes for studies in organic chemistry and drug discovery.

Basic Information

Product Name	(-)-Trimeprazine
CAS No.	2256-27-1
Molecular Formula	C18H22N2S
Molecular Weight	298.45 g/mol
Synonyms	(-)-Alimemazine; Levomepromazine impurity C; (S)-Trimeprazine; (2S)-10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine; L-Trimeprazine; (-)-10-(3-Dimethylamino-2-methylpropyl)phenothiazine; (S)-10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine
EINECS	Contact for details

Quality Control

Our (-)-Trimeprazine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including chiral purity determination and impurity profiling via advanced techniques like HPLC. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or pharmacopeial requirements (e.g., USP/EP reference standards).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.