Description

Flumethasone CAS NO 2135-17-3 is a synthetic glucocorticoid corticosteroid with potent anti-inflammatory and immunosuppressive properties. This compound is a critical active pharmaceutical ingredient (API) for the formulation of high-efficacy topical and veterinary medicinal products. It is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for dermatological conditions and inflammatory disorders. Our supply ensures the high purity and consistency required for sensitive pharmaceutical applications.

Application

• Pharmaceutical API: Core ingredient in topical creams, ointments, and lotions for treating eczema, psoriasis, and dermatitis.
• Veterinary Medicine: Key component in ear drops and topical solutions for managing otitis externa and skin inflammation in companion animals.
• Dermatological Research: Used as a reference standard and active agent in preclinical and clinical studies for new anti-inflammatory therapies.
• Compound Formulations: Employed in combination with antimicrobial agents in medicated preparations for enhanced therapeutic effect.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.

Basic Information

Product Name	Flumethasone
CAS No.	2135-17-3
Molecular Formula	C22H28F2O5
Molecular Weight	410.46 g/mol
Synonyms	Flumethasone; 6α,9α-Difluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 6α,9α-Difluoroprednisolone 16α-methyl; NSC-107679; SH 742; Flumetasone; Flumethasonum; Flumetason
EINECS	218-369-6

Quality Control

Our Flumethasone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) that detail all test results against stringent in-house specifications, which are aligned with major pharmacopoeial standards. Our commitment ensures the material is suitable for GMP manufacturing and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.