Description

9-Fluoro-11Beta,17Alpha-Dihydroxy-17-(S)-Lactoylandrosta-1,4-Dien-3-One 17Beta-Acetate is a high-purity synthetic steroid derivative, primarily valued as a critical pharmaceutical intermediate in the synthesis of advanced corticosteroid and anti-inflammatory APIs. Its complex fluorinated androstane structure makes it essential for developing potent topical and systemic medications. This compound is specifically targeted for use by pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent glucocorticoid receptor agonists and anti-inflammatory steroid drugs.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for novel corticosteroid-based therapies targeting dermatological, respiratory, and autoimmune conditions.
• Biochemical Research: Serves as a reference standard and tool compound in pharmacological studies investigating steroid hormone receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Employed in advanced organic synthesis for introducing specific fluorinated androstane motifs into complex molecular architectures.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the commercial manufacturing of steroid-based pharmaceuticals.

Basic Information

Product Name	9-Fluoro-11Beta,17Alpha-Dihydroxy-17-(S)-Lactoylandrosta-1,4-Dien-3-One 17Beta-Acetate
CAS No.	2119-75-7
Molecular Formula	C24H29FO7
Molecular Weight	448.48 g/mol
Synonyms	9α-Fluoro-11β,17α,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-acetate; Fluocinolone Acetonide Acetate; 6α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-acetate; Fluocinolone Acetonide 21-Acetate; 6α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-acetate; NSC 92339; RS-2252; SQ-15102
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,17Alpha-Dihydroxy-17-(S)-Lactoylandrosta-1,4-Dien-3-One 17Beta-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your GMP-compliant manufacturing and R&D processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.