Description

2-Chloro-4-Fluoronitrobenzene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a nitrobenzene ring, makes it a highly valuable intermediate for introducing specific functional groups and electronic properties into target molecules. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients, complex heterocycles, and other fine chemicals.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Building block for the production of advanced agrochemicals, such as herbicides and pesticides.
• Precursor in the manufacture of liquid crystal materials and other specialty electronic chemicals.
• Starting material for the synthesis of dyes, pigments, and other complex aromatic compounds.
• Versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Used in academic and industrial research for exploring novel fluorinated organic molecules.

Basic Information

Product Name	2-Chloro-4-Fluoronitrobenzene
CAS No.	2106-50-5
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	1-Chloro-2-fluoro-5-nitrobenzene; 2-Chloro-1-fluoro-4-nitrobenzene; 2-Fluoro-4-chloronitrobenzene; 4-Chloro-2-fluoronitrobenzene; 4-Fluoro-2-chloronitrobenzene; Benzene, 2-chloro-1-fluoro-4-nitro-; 2-Chloro-4-fluoronitrobenzene
EINECS	218-278-1

Quality Control

Our 2-Chloro-4-Fluoronitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.