Description

2,4-Dichloro-5-Fluoronitrobenzene is a high-purity halogenated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs) requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the dichloro-fluoro motif contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing high-performance, light-fast dyes and organic pigments.
• Material Science Research: Employed in the development of novel liquid crystals, organic semiconductors, and other functional materials.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups make it an excellent candidate for selective substitution reactions in fine chemical production.

Basic Information

Product Name	2,4-Dichloro-5-Fluoronitrobenzene
CAS No.	2105-59-1
Molecular Formula	C6H2Cl2FNO2
Molecular Weight	209.99 g/mol
Synonyms	1,3-Dichloro-4-fluoro-5-nitrobenzene; 4-Fluoro-3,5-dichloronitrobenzene; 5-Fluoro-2,4-dichloronitrobenzene; Benzene, 2,4-dichloro-5-fluoro-1-nitro-; 2,4-Dichloro-5-fluoro-1-nitrobenzene; NSC 403106
EINECS	218-267-4

Quality Control

Every batch of 2,4-Dichloro-5-Fluoronitrobenzene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.