Description

Phenbenzamine Hydrochloride CAS NO 2045-52-5 is a pharmaceutical-grade organic compound belonging to the class of antihistamines and anticholinergics. It serves as a critical active pharmaceutical ingredient (API) and a valuable intermediate in the synthesis of specialized therapeutic agents. This high-purity compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the key therapeutic component in antihistamine and anticholinergic drug formulations.
• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of more complex drug molecules and analogs.
• Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies targeting histamine and acetylcholine receptors.
• Veterinary Medicine: Potential application in veterinary pharmaceutical products for managing allergic reactions and certain autonomic disorders.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial batches.

Basic Information

Product Name	Phenbenzamine Hydrochloride
CAS No.	2045-52-5
Molecular Formula	C17H21ClN2 • HCl
Molecular Weight	321.27 g/mol
Synonyms	Phenbenzamine HCl; N-Benzyl-N',N'-dimethyl-N-phenylethylenediamine Hydrochloride; 2-[(Benzylphenylamino)methyl]-N,N-dimethylethanamine Hydrochloride; N,N-Dimethyl-N'-benzyl-N'-phenylethylenediamine Hydrochloride; Benzylphenamine Hydrochloride; Antergan (historical brand); RP 2339
EINECS	218-067-3

Quality Control

Our Phenbenzamine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by FT-IR and NMR, to ensure it meets stringent pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.